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Closed-Loop Technologies - Coordinator: Lutz Wiegrebe

Recent hard- and software advances make it possible to integrate rapid online data analysis, adaptive sampling techniques, and computational modelling into the design of neuroscience experiments. The broad range of such approaches at the Bernstein Center Munich – from dynamic clamp (A2) and iso-response methods (A3, B2) to virtual reality (A3, B3, B5, D1, D2, PC, PD) – makes it possible to discuss methodological issues and transfer expert knowledge between different levels of investigation. The primary goal is to improve the design of experiments, addressing issues such as optimal spatio/temporal averaging of data and the stability of experimental feedback loops, which, in turn, may lead to new insight about closed-loop situations in neurobiological and artificial systems, the interaction of visual processing and eye movements (B1), and course control (C3).

Overview of relevant projects

A2: Dissecting the role of ionic currents in object localization using an advanced dynamic-clamp system (J. Benda, W. Hemmert & H.R. Polder)

A3: New methods to study visual influences on auditory processing (B. Grothe, A. Herz, C. Leibold & H. Luksch)

B2: Coding of spatial and temporal information in a population of specialized auditory interneurons (A. Herz & J. Benda)

B3: Auditory invariance against space-induced reverberation (L. Wiegrebe, B. Grothe & C. Leibold)

B5: Temporal aspects of spatial memory consolidation (S. Gais, S. Glasauer & C. Leibold)

B-T2:Learning the reflection characteristics of rooms (B.U. Seeber & M. Kleinsteuber)

B-T3: Proprioceptive stabilization of the auditory world (P. MacNeilage, U. Firzlaff & L. Wiegrebe)

C3: Optic Flow Decoding - Circuit Analysis in the Fly and Implementation on a Robofly (J. Conradt, M. Buss & A. Borst)

C-T1: Sensor Fusion in Cortical Circuits: Modeling and Behavioral Experiments in Man and Machine (Jörg Conradt & Stefan Glasauer)

D1: The effect of aging on basic aspects of spatial orientation and navigation (S. Glasauer & T. Brandt)

D2: Visual-vestibular and visuo-visual cortical interaction (T. Brandt, L. van Hemmen & S. Glasauer)